RegisterLogin

CAY10573

CAT: 0931-T37829-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T37829-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
853652-40-1
Target
PPAR|||Others
Related Pathways
Others|||DNA Damage/DNA Repair|||Metabolism
Bioactivity
The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPAR?, ?, and ? with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPAR?, ?, and ? with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPAR? than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM) .
Smiles
C(CC)C=1C2=C(C=C(C(=O)C3=CC=CC=C3)C=C2)C=CC1OCCCOC=4C=C5C(=CC4)N(CC(O)=O)C=C5
Molecular Formula
C33H31NO5
Molecular Weight
521.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T36882-01CAY10773
T26958-01CAY10583
T36702-01CAY10753
T26957-01CAY10575
T35987-01CAY10563
T36963-01CAY10503
T36460-01CAY10736
T7280-01CAY10594
T37830-01CAY10599
T36550-01CAY10535

Alternative Products

CatalogName
MBS5798633CAY10573

Popular Products