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AZ-GHS-22

CAT: 0931-T37412-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T37412-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1143020-91-0
Target
Others, GHSR
Related Pathways
GPCR/G Protein, Others
Bioactivity
AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1It binds to GHS-R1a with an IC50value of 0.77 nM. AZ-GHS-22 decreases food intake in mice by 54% in the first two hours after administration of a 100 mg/kg dose.
Smiles
N(C(NC(=O)C1=CC(=CC=C1Cl)N2CCOCC2)=O)C=3SC=4C(N3)=CC=C(S(CCCN5CCN(C)CC5)(=O)=O)C4
Molecular Formula
C27H33ClN6O5S2
Molecular Weight
621.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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