AZ'6421

• Target:

  PROTACs|||Estrogen Receptor/ERR|||Others

• Related Pathways:

  Others|||Endocrinology/Hormones|||PROTAC

• Bioactivity:

  AZ'6421, functioning as a Proteolysis Targeting Chimera (PROTAC), selectively degrades estrogen receptor alpha, demonstrating potent anti-tumor activity by inhibiting uncontrolled cellular proliferation characteristic of malignant diseases. This compound holds promise for cancer research, including breast cancer applications [1].

• Smiles:

  C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(C)(C)F)c1c(F)cc(OCCCOCCCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)cc1F

• Molecular Formula:

  C52H65F3N6O7S

• Molecular Weight:

  975.17

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2361115-35-5