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Desmethyl Bosentan

CAT: 0931-T37351-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T37351-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
253688-61-8
Target
Cytochromes P450, Others, Drug Metabolite
Related Pathways
Others, Metabolism
Bioactivity
Desmethyl bosentan, an active metabolite of the endothelin receptor antagonist bosentan, activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay at a concentration of 25 μM.
Smiles
CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1nc(nc(OCCO)c1Oc1ccccc1O)-c1ncccn1
Molecular Formula
C26H27N5O6S
Molecular Weight
537.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
D291275Desmethyl Bosentan
CS-O-10023Hydroxy Desmethyl Bosentan
163689Desmethyl Bosentan-d4
RM-B191408-01Bosentan O-Desmethyl Impurity
AR-B01912-01Hydroxy Desmethyl Bosentan-d4
AR-B01910-01Hydroxy O-Desmethyl Bosentan
RM-B191407-01Bosentan Hydroxymethyl O-Desmethyl Impurity
AR-B07568-01Hydroxy O-Desmethyl Bosentan Sodium Salt
D3220-86GDesmethyl Bosentan (4- (1,1-dimethylethyl) -N-[6- (2-hydroxyethoxy) -5- (2-hydroxyphenoxy) [2,2’-bipyrimidin]-4-yl]benzenesulfonamide)
MBS6089332-01Desmethyl Bosentan (4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide)

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