Desmethyl-QCA276

• CAS Number :

  2126819-55-2

• Target :

  Others|||Ligands for Target Protein for PROTAC

• Related Pathways :

  Others|||PROTAC

• Bioactivity :

  Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].

• Smiles :

  C(#CC=1SC2=C(C1CC=3C=CC=CC3)COCC4=NN=C(N42)C)C=5C=NNC5

• Molecular Formula :

  C21H17N5OS

• Molecular Weight :

  387.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C