Desmethyl-QCA276

CAT: 0931-T18601-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T18601-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2126819-55-2
Target
Others|||Ligands for Target Protein for PROTAC
Related Pathways
Others|||PROTAC
Bioactivity
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
Smiles
C(#CC=1SC2=C(C1CC=3C=CC=CC3)COCC4=NN=C(N42)C)C=5C=NNC5
Molecular Formula
C21H17N5OS
Molecular Weight
387.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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