Desmethyl-QCA276

• Target:

  Others|||Ligands for Target Protein for PROTAC

• Related Pathways:

  Others|||PROTAC

• Bioactivity:

  Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].

• Smiles:

  C (#CC=1SC2=C (C1CC=3C=CC=CC3) COCC4=NN=C (N42) C) C=5C=NNC5

• Molecular Formula:

  C21H17N5OS

• Molecular Weight:

  387.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2126819-55-2