GI-530159

• Target :

  Others|||Potassium Channel

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  TREK1 and TREK2 channel activator (EC50 = 0.76 ?M in Rb efflux assay in TREK1-expressing CHO cells) . Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity in vitro.

• Smiles :

  Nc1ccc(Oc2ccc(cc2)C(c2ccc(Oc3ccc(N)cc3)cc2)(C(F)(F)F)C(F)(F)F)cc1

• Molecular Formula :

  C27H20F6N2O2

• Molecular Weight :

  518.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  69563-88-8