AS-99 TFA
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AS-99 TFA
Target:
Others|||Apoptosis|||Histone MethyltransferaseRelated Pathways:
Chromatin/Epigenetic|||Apoptosis|||OthersBioactivity:
AS-99 TFA is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 ?M, Kd= 0.89 ?M) with anti-leukemic activity. It blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1].Shipping Conditions:
Cool packStorage Temperature:
-20°C