Products for Research Use Only

AS-99 TFA

CAT: 0931-T36978-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36978-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Apoptosis, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Apoptosis, Others
Bioactivity
AS-99 TFA is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. It blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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