KR-32568

• Target:

  Sodium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  0.9991

• Bioactivity:

  KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 ?M, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.

• Smiles:

  CC1=C (C=2OC (C (NC (=N) N) =O) =CC2) C=C (F) C=C1

• Molecular Formula:

  C13H12FN3O2

• Molecular Weight:

  261.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  852146-73-7