KR-32568

• Target :

  Sodium Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9991

• Bioactivity :

  KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 ?M, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.

• Smiles :

  CC1=C(C=2OC(C(NC(=N)N)=O)=CC2)C=C(F)C=C1

• Molecular Formula :

  C13H12FN3O2

• Molecular Weight :

  261.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  852146-73-7