KR-32568

CAT: 0931-T36569-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T36569-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
852146-73-7
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9991
Bioactivity
KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 ?M, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.
Smiles
CC1=C(C=2OC(C(NC(=N)N)=O)=CC2)C=C(F)C=C1
Molecular Formula
C13H12FN3O2
Molecular Weight
261.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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