PR-104

• Target :

  Others|||DNA Alkylator/Crosslinker

• Related Pathways :

  Others|||DNA Damage/DNA Repair

• Bioactivity :

  PR-104 is a highly specific hypoxia-activated agent that cross-links DNA, enabling its application in various tumor xenograft models. Functioning as a pre-prodrug of nitrogen mustard, PR-104 undergoes efficient conversion to the dinitrobenzamide mustards alcohol form, known as PR-104A[1].

• Smiles :

  N(CCOS(C)(=O)=O)(CCBr)C1=C(C(NCCOP(=O)(O)O)=O)C=C(N(=O)=O)C=C1N(=O)=O

• Molecular Formula :

  C14H20BrN4O12PS

• Molecular Weight :

  579.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  851627-62-8