IKP-104

• Target:

  Microtubule Associated

• Related Pathways:

  Cytoskeletal Signaling

• Bioactivity:

  IKP-104 is a microtubule/tubulin inhibitor (IC50 = 1.31 ?M) that halts cells in mitosis and the M phase by inhibiting microtubule assembly and inducing cytoskeleton microtubule depolymerization. It suppresses the growth of both murine and human tumor cell lines, exhibiting antitumor effects in mouse ascites tumor and lung cancer models. IKP-104 is applicable in research on cancers such as leukemia, lung cancer, and melanoma.

• Smiles:

  O=C1C=C(C=2C=CC=CC2)N(C=3C=C(OC)C=C(OC)C3Cl)C(C=4C=CC(F)=CC4)=C1C

• Molecular Formula:

  C26H21ClFNO3

• Molecular Weight:

  449.9

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  114231-14-0