Products for Research Use Only
RegisterLogin

Miro1 Reducer

CAT: 0931-T35670-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T35670-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2624336-91-8
Target
Others
Related Pathways
Others
Bioactivity
Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1) . Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM) . Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
Smiles
Cl.O=C(NC1=CC=C(C=C1)NC2=NC=NC(=C2)N3C=NC=C3)NC=4C=CC=C(F)C4
Molecular Formula
C20H17FN7OCl
Molecular Weight
425.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Miro1 Reducer
CAS Number2624336-91-8
PubChem CID154828685
IUPAC Name1-(3-fluorophenyl)-3-[4-[(6-imidazol-1-ylpyrimidin-4-yl)amino]phenyl]urea;hydrochloride
Molecular FormulaC20H17ClFN7O
Molecular Weight425.8
Topological Polar Surface Area96.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count30
Formal Charge0
Complexity531
SMILES
C1=CC(=CC(=C1)F)NC(=O)NC2=CC=C(C=C2)NC3=CC(=NC=N3)N4C=CN=C4.Cl
InChI
InChI=1S/C20H16FN7O.ClH/c21-14-2-1-3-17(10-14)27-20(29)26-16-6-4-15(5-7-16)25-18-11-19(24-12-23-18)28-9-8-22-13-28;/h1-13H,(H,23,24,25)(H2,26,27,29);1H
InChIKey
UKXRHSHXZHFFTA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Miro1 Reducer
CAS: 2624336-91-8
CID: 154828685
Formula: C20H17ClFN7O
MW: 425.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight425.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass425.1167140
Monoisotopic Mass425.1167140
Topological Polar Surface Area96.8 Ų
Heavy Atom Count30
Formal Charge0
Complexity531
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
T37167-01Reduced Haloperidol
TP3411-01Somatostatin-14 (reduced)
TMIH-0488-01Reduced Haloperidol-d4
T1085-01L-Glutathione reduced
T77253-01β-Nicotinamide adenine dinucleotide reduced dipotassium
CB0130SReduced Glutathione Assay Kit (Spectrophotometry)
CB0130MReduced Glutathione Assay Kit (Microanalysis)

Alternative Products

CatalogName
HY-163172-01Miro1 Reducer
E55A14977Miro1 Antibody
NXA30010RunBlue DTT Reducer
U10132Reducer for Sample Tube
FL0RDC001DISPENSER FLOW REDUCER
U10085Serum Tray with Reducer
TS414409P5MIRO1 (RHOT1) CytoSection
1602851T-Reducer Connector with 400
1216916Reducer Connector, Straight, Classic
12115545060-6005, Reducer Connector, Straight

Popular Products