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Miro1 Reducer

CAT: 0931-T35670-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T35670-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2624336-91-8
Target
Others
Related Pathways
Others
Bioactivity
Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1) . Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 ?M) . Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
Smiles
Cl.O=C(NC1=CC=C(C=C1)NC2=NC=NC(=C2)N3C=NC=C3)NC=4C=CC=C(F)C4
Molecular Formula
C20H17FN7OCl
Molecular Weight
425.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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