Miro1 Reducer

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1) . Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 ?M) . Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.

• Smiles:

  Cl.O=C (NC1=CC=C (C=C1) NC2=NC=NC (=C2) N3C=NC=C3) NC=4C=CC=C (F) C4

• Molecular Formula:

  C20H17FN7OCl

• Molecular Weight:

  425.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2624336-91-8