(±) 13 (14) -EpDPA

CAT: 0931-T35496-01Size: 25 µgDry Ice: NoHazardous: No

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CAT#:0931-T35496-01Size:25 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

895127-64-7

Target

Cytochromes P450, Others

Related Pathways

Metabolism, Others

Bioactivity

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±) 13 (14) -EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±) 13 (14) -EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±) 13 (14) -EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.

Smiles

CC\C=C/C\C=C/CC1OC1C\C=C/C\C=C/C\C=C/CCC(O)=O

Molecular Formula

C22H32O3

Molecular Weight

344.495

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T37235	(±) 16 (17) -EpDPA
T35493-01	(±) 10 (11) -EpDPA
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T204601-01	(±) 13,14-DiHDoTrE
TN11151-01	13,14-EDT
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Alternative Products

Catalog	Name
GTR19222638-01	(±) 13 (14) -EpDPA
MBS5796838	(+/-)13(14)-EpDPA
HY-130550-01	(±) 7 (8) -EpDPA
MBS5798181	(+/-)16(17)-EpDPA
MBS5796839	(+/-)7(8)-EpDPA
MBS5796835	(+/-)10(11)-EpDPA
GTR19222641-01	(±) 10 (11) -EpDPA
HY-165071	(±) 16 (17) -EpDPA
MBS5798184	(+/-)19(20)-EpDPA
GTR19222583-01	19R (20S) -EpDPA

(±) 13 (14) -EpDPA

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