(±) 10 (11) -EpDPA

CAT: 0931-T35493-01Size: 25 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T35493-01Size:25 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

895127-65-8

Target

Others, Epoxide Hydrolase

Related Pathways

Others, Metabolism

Bioactivity

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±) 10 (11) -EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±) 10 (11) -EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.

Smiles

CC\C=C/C\C=C/C\C=C/CC1OC1C\C=C/C\C=C/CCC(O)=O

Molecular Formula

C22H32O3

Molecular Weight

344.495

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T35497-01	(±) 7 (8) -EpDPA
T35496-01	(±) 13 (14) -EpDPA
T37238-01	(±) 19 (20) -EpDPA
T36218-01	19R (20S) -EpDPA
T37235	(±) 16 (17) -EpDPA
T84936-01	10,11-dihydro-10,11-dihydroxy Carbamazepine
T37241-01	(±) 4 (5) -EpDPA methyl ester
T72859-01	11β-HSD1-IN-10
T75458-01	(-) -10,11-Dihydroxyfarnesol
TN7580-01	10,11-EDT

Alternative Products

Catalog	Name
MBS5796835	(+/-)10(11)-EpDPA
GTR19222641-01	(±) 10 (11) -EpDPA
HY-130550-01	(±) 7 (8) -EpDPA
MBS5798181	(+/-)16(17)-EpDPA
MBS5796839	(+/-)7(8)-EpDPA
HY-165071	(±) 16 (17) -EpDPA
MBS5798184	(+/-)19(20)-EpDPA
GTR19222638-01	(±) 13 (14) -EpDPA
GTR19222583-01	19R (20S) -EpDPA
MBS5796838	(+/-)13(14)-EpDPA

(±) 10 (11) -EpDPA

Related Products

Alternative Products

Popular Products