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(±) 7 (8) -EpDPA

CAT: 0931-T35497-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T35497-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
895127-66-9
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±) 7 (8) -EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±) 7 (8) -EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±) 7 (8) -EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.
Smiles
CC\C=C/C\C=C/C\C=C/C\C=C/CC1OC1C\C=C/CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.495
Shipping Conditions
Ice Packs
Storage Temperature
-20°C