(E/Z) -THZ1 2HCl

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.9951

• Bioactivity:

  THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.

• Smiles:

  Cl.Cl.CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

• Molecular Formula:

  C31H30Cl3N7O2

• Molecular Weight:

  638.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2095433-94-4