THZ1

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.9927

• Bioactivity :

  THZ1 (CDK7 inhibitor) is a selective covalent inhibitor of CDK7, exhibiting binding affinity to the cysteine residue located at the outer end of the classical kinase domain, thus conferring high selectivity for CDK7, with an IC50 of 3.2 nM.

• Smiles :

  CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

• Molecular Formula :

  C31H28ClN7O2

• Molecular Weight :

  566.05

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1604810-83-4