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THZ1

CAT: 0931-T3664-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T3664-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1604810-83-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9927
Bioactivity
THZ1 (CDK7 inhibitor) is a selective covalent inhibitor of CDK7, exhibiting binding affinity to the cysteine residue located at the outer end of the classical kinase domain, thus conferring high selectivity for CDK7, with an IC50 of 3.2 nM.
Smiles
CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1
Molecular Formula
C31H28ClN7O2
Molecular Weight
566.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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