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THZ1-R

CAT: 0931-T13153Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T13153Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1621523-07-6
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, losing its ability to covalently bind to the C312 cysteine residue of CDK7. Its CDK7 inhibitory activity is weaker than that of THZ1.
Smiles
O=C(NC=1C=CC=C(C1)NC=2N=CC(Cl)=C(N2)C3=CNC=4C=CC=CC43)C5=CC=C(C=C5)NC(=O)CCCN(C)C
Molecular Formula
C31H30ClN7O2
Molecular Weight
568.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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