TP-238

CAT: 0931-T34907-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T34907-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2415263-04-4

Target

Others, Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic, Others

Bioactivity

TP-238, a potent and selective dual CECR2/BPTF probe, exhibits IC50 values of 30 nM and 350 nM, respectively. Additionally, it inhibits BRD9 with a pIC50 of 5.9, demonstrating lesser activity against another 338 kinases [1] [2].

Smiles

N(CCCN1C=CC=N1)C2=CC(=NC(S(C)(=O)=O)=N2)C3=CC=C(OCCCN(C)C)C=C3

Molecular Formula

C22H30N6O3S

Molecular Weight

458.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine

CAS Number	2415263-04-4
PubChem CID	137796292
IUPAC Name	6-[4-[3-(dimethylamino)propoxy]phenyl]-2-methylsulfonyl-N-(3-pyrazol-1-ylpropyl)pyrimidin-4-amine
Molecular Formula	C22H30N6O3S
Molecular Weight	458.6
XLogP	2.4
Topological Polar Surface Area	111
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	12
Heavy Atom Count	32
Formal Charge	0
Complexity	636

SMILES

CN(C)CCCOC1=CC=C(C=C1)C2=CC(=NC(=N2)S(=O)(=O)C)NCCCN3C=CC=N3

InChI

InChI=1S/C22H30N6O3S/c1-27(2)13-6-16-31-19-9-7-18(8-10-19)20-17-21(26-22(25-20)32(3,29)30)23-11-4-14-28-15-5-12-24-28/h5,7-10,12,15,17H,4,6,11,13-14,16H2,1-3H3,(H,23,25,26)

InChIKey

MSIJJXOWLFOYIN-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2415263-04-4

CID: 137796292

Formula: C22H30N6O3S

MW: 458.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	458.6
XLogP3	2.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	12
Exact Mass	458.21001001
Monoisotopic Mass	458.21001001
Topological Polar Surface Area	111 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	636
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
MBS3607056	TP-238
6670/10	TP 238
HY-114205A-01	TP-238 (hydrochloride)
574026	TP-238 HCl
MBS5800371-01	TP-238 hydrochloride
A24419-100	TP-238 hydrochloride 100mg
A24419-50	TP-238 hydrochloride 50mg
A24419-5	TP-238 hydrochloride 5mg
A24419-10	TP-238 hydrochloride 10mg
FT28014-01	TCN 238

TP-238

Chemical Information

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