Ro 67-7476

• Target :

  GluR

• Related Pathways :

  Neuroscience

• Purity :

  0.9969

• Bioactivity :

  Ro 67-7476 is a positive allosteric modulator of mGluR1, which can enhance the calcium release induced by glutamate in HEK293 cells expressing rat mGluR1a. The EC50 is 60.1 nM. It is a P-ERK1/2 agonist, and can activate ERK1/2 phosphorylation without the addition of exogenous glutamate (EC50 = 163.3 nM) .

• Smiles :

  Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1

• Molecular Formula :

  C17H18FNO2S

• Molecular Weight :

  319.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  298690-60-5