Products for Research Use Only
RegisterLogin

MK-3281

CAT: 0931-T33432-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T33432-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
886041-60-7
Target
Others, HCV Protease
Related Pathways
Others, Proteases/Proteasome, Microbiology/Virology
Bioactivity
MK-3281 is a potent, orally bioavailable hepatitis C virus NS5B polymerase finger-loop inhibitor. It is also an inhibitor of attractive molecular properties with good potency in HCV subgenomic replication trials and suitable for clinical candidates.
Smiles
N(CCN(C)C)(C)[C@@H]1CN2C(=C(C=3C2=CC(C(O)=O)=CC3)C4CCCCC4)C=5C(OC1)=CC=CC5
Molecular Formula
C29H37N3O3
Molecular Weight
475.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Mk 3281
CAS Number886041-60-7
PubChem CID49800096
IUPAC Name(10R)-19-cyclohexyl-10-[2-(dimethylamino)ethyl-methylamino]-8-oxa-12-azatetracyclo[10.7.0.02,7.013,18]nonadeca-1(19),2,4,6,13(18),14,16-heptaene-15-carboxylic acid
Molecular FormulaC29H37N3O3
Molecular Weight475.6
XLogP3.3
Topological Polar Surface Area57.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count35
Formal Charge0
Complexity711
SMILES
CN(C)CCN(C)[C@@H]1CN2C3=C(C=CC(=C3)C(=O)O)C(=C2C4=CC=CC=C4OC1)C5CCCCC5
InChI
InChI=1S/C29H37N3O3/c1-30(2)15-16-31(3)22-18-32-25-17-21(29(33)34)13-14-23(25)27(20-9-5-4-6-10-20)28(32)24-11-7-8-12-26(24)35-19-22/h7-8,11-14,17,20,22H,4-6,9-10,15-16,18-19H2,1-3H3,(H,33,34)/t22-/m1/s1
InChIKey
YQUCBFIQSJVCOR-JOCHJYFZSA-N
Chemical Structure
2D Structure
2D structure of Mk 3281
CAS: 886041-60-7
CID: 49800096
Formula: C29H37N3O3
MW: 475.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight475.6
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass475.28349205
Monoisotopic Mass475.28349205
Topological Polar Surface Area57.9 Ų
Heavy Atom Count35
Formal Charge0
Complexity711
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T9901A-974-01MK-4721
T9901A-857-01MK-4166
T2126-01MK-5046
T16089-01MK-0674
T71566-01MK-7445
T71165-01MK-1421
T2471-01MK-8745
T86907-01MK-8527
TQ0219-01MK-8033
T24478-01MK-8141

Alternative Products

CatalogName
MBS5782979MK-3281
324068-01MK
NBP3-07155-100ugMouse Monoclonal TYRP1 Antibody (TYRP1/3281)
167912Midkine (MK, MK1, MK-1, MK 1) discontinued
MBS131426MK-4101 (MK 4101; MK4101)
NBP3-08897PEMouse Monoclonal TYRP1 Antibody (TYRP1/3281) [PE]
NBP3-08897PCPMouse Monoclonal TYRP1 Antibody (TYRP1/3281) [PerCP]
NBP3-08897HMouse Monoclonal TYRP1 Antibody (TYRP1/3281) [HRP]
NBP3-08897APCMouse Monoclonal TYRP1 Antibody (TYRP1/3281) [Allophycocyanin]
NBP3-08897FMouse Monoclonal TYRP1 Antibody (TYRP1/3281) [FITC]

Popular Products