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JH-IX-179

CAT: 0931-T32288-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T32288-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
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Bioactivity
JH-IX-179 is a novel type I ATP competitive and highly selective FLT3 inhibitor. JH-IX-179 is much more selective for FLT3 and FLT3 mutants than for Kronani. In addition, JH-IX-179 showed little human serum protein binding and effectively inhibited autophosphorylation of FLT3 and activity of downstream signaling molecules of FLT3-D835Y and FLT3-ITD.
Smiles
O=C1C2=C(NC3=C2C=CC(C4=CNN=C4)=C3)C5=C1C=CC(C6=CN(CCCN(C)C)N=C6)=C5
Molecular Formula
C26H24N6O
Molecular Weight
436.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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