IMG-2005

• Target:

  TLR

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  IMG-2005 acts as an inhibitor of the TLR signaling pathway by mimicking the Toll/interleukin-1 receptor (TIR) domain of MyD88. This action prevents the homodimerization of MyD88, mitigating damage to tracheal epithelial cells and averting the onset of pulmonary immune diseases.

• Smiles:

  C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(NCC(N[C@@H]([C@@H](C)O)C(O)=O)=O)=O)CCC4)CC(C)C)=O)C(C)C)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=5C=6C(NC5)=CC=CC6

• Molecular Formula:

  C140H227N45O33S

• Molecular Weight:

  3100.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1229954-79-3