IMG-2005

CAT: 0931-TP2839-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2839-01Size:10 mg
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CAS Number
1229954-79-3
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
IMG-2005 acts as an inhibitor of the TLR signaling pathway by mimicking the Toll/interleukin-1 receptor (TIR) domain of MyD88. This action prevents the homodimerization of MyD88, mitigating damage to tracheal epithelial cells and averting the onset of pulmonary immune diseases.
Smiles
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(NCC(N[C@@H]([C@@H](C)O)C(O)=O)=O)=O)CCC4)CC(C)C)=O)C(C)C)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C140H227N45O33S
Molecular Weight
3100.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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