AZD-5672

• Target:

  CCR|||P-gp|||Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Neuroscience|||Microbiology/Virology|||GPCR/G Protein|||Immunology/Inflammation

• Purity:

  0.981

• Bioactivity:

  AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7.3 ?M and 32 ?M. AZD-5672 can be used in studies about rheumatoid arthritis.

• Smiles:

  CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(F)c2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O

• Molecular Formula:

  C32H38F2N2O5S2

• Molecular Weight:

  632.78

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  780750-65-4