SC-2001

• Target:

  Others|||STAT|||Apoptosis|||Bcl-2 Family

• Related Pathways:

  Stem Cells|||JAK/STAT signaling|||Apoptosis|||Others

• Bioactivity:

  SC-2001 is a MCL-1 inhibitor. SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma.

• Smiles:

  C(C=1NC(C2=CC=3C(N2)=CC=C(Br)C3)=CC1OC)=C4C=CC=N4

• Molecular Formula:

  C18H14BrN3O

• Molecular Weight:

  368.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1383727-17-0