Cyclopamine

• Target :

  Endogenous Metabolite|||Hedgehog/Smoothened|||Smo

• Related Pathways :

  Metabolism|||GPCR/G Protein|||Stem Cells

• Purity :

  0.9966

• Bioactivity :

  Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.

• Smiles :

  [H][C@@]12CC3O[C@]4([H])C[C@H](C)CN[C@@]4([H])[C@@H](C)[C@@]3([H])C(C)=C1C[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

• Molecular Formula :

  C27H41NO2

• Molecular Weight :

  411.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  4449-51-8