Cyclopamine

• Target:

  Endogenous Metabolite|||Hedgehog/Smoothened|||Smo

• Related Pathways:

  Metabolism|||GPCR/G Protein|||Stem Cells

• Purity:

  0.9966

• Bioactivity:

  Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.

• Smiles:

  [H][C@@]12CC3O[C@]4([H])C[C@H](C)CN[C@@]4([H])[C@@H](C)[C@@]3([H])C(C)=C1C[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

• Molecular Formula:

  C27H41NO2

• Molecular Weight:

  411.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  4449-51-8