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Ono 1301

CAT: 0931-T28240-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28240-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
176391-41-6
Target
Others, Prostaglandin Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others
Bioactivity
Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only with induction of HGF but also by Ono 1301 itself. It also works through promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.
Smiles
C(CO/N=C(\C1=CC=CC=C1)/C=2C=CC=NC2)C=3C=4C(=C(OCC(O)=O)C=CC4)CCC3
Molecular Formula
C26H24N2O4
Molecular Weight
428.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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