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NMK-TD-100

CAT: 0931-T28179-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28179-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1252802-38-2
Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Apoptosis, Others
Bioactivity
NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 μM.
Smiles
O(C)C=1C=C(C=2SC(C=3C=4C(NC3)=CC=CC4)=NN2)C=C(OC)C1OC
Molecular Formula
C19H17N3O3S
Molecular Weight
367.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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