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DCBP-1

CAT: 0931-T9370-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9370-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2484739-25-3
Target
PROTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic
Purity
0.9912
Bioactivity
DCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
Smiles
C(NC)(=O)N1CC=2C(=NN(C2CC1)C3CCN(C(CCOCCOCCOCCOCCNC=4C=C5C(=CC4)C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=O)CC3)N7C=8C(=CC(=C(C(F)F)C8)C9=CN(C)N=C9)CCC7
Molecular Formula
C51H63F2N11O10
Molecular Weight
1028.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C