Products for Research Use Only
RegisterLogin

CNS-5161

CAT: 0931-T27055-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T27055-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
160754-76-7
Target
Others, iGluR
Related Pathways
Others, Neuroscience, Membrane transporter/Ion channel
Bioactivity
CNS-5161 is an NMDA antagonist.
Smiles
N(C(N(C)C1=CC(SC)=CC=C1)=N)C2=CC(SC)=CC=C2Cl
Molecular Formula
C16H18ClN3S2
Molecular Weight
351.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Cns 5161

CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.

CAS Number160754-76-7
PubChem CID192711
IUPAC Name2-(2-chloro-5-methylsulfanylphenyl)-1-methyl-1-(3-methylsulfanylphenyl)guanidine
Molecular FormulaC16H18ClN3S2
Molecular Weight351.9
XLogP4.2
Topological Polar Surface Area92.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity380
SMILES
CN(C1=CC(=CC=C1)SC)C(=NC2=C(C=CC(=C2)SC)Cl)N
InChI
InChI=1S/C16H18ClN3S2/c1-20(11-5-4-6-12(9-11)21-2)16(18)19-15-10-13(22-3)7-8-14(15)17/h4-10H,1-3H3,(H2,18,19)
InChIKey
JHVHEDNLONERHY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cns 5161
CAS: 160754-76-7
CID: 192711
Formula: C16H18ClN3S2
MW: 351.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight351.9
XLogP34.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass351.0630676
Monoisotopic Mass351.0630676
Topological Polar Surface Area92.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity380
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T69411-01CNS-5788
T84812-01CNS-11
T25726-01Lilly 51641
T68370-01Sdz 51641
T10966-01DC-5163
T127077-01Compound STOCK1N-51619
T28766-01SGE-516
T13339-01Wf-516

Alternative Products

CatalogName
HY-101809ACNS 5161
GTR19197865-01CNS-5161
MBS3614773-01CNS-5161 hydrochloride
A20308-50CNS-5161 hydrochloride 50mg
A20308-10CNS-5161 hydrochloride 10mg
A20308-5CNS-5161 hydrochloride 5mg
A20308-25CNS-5161 hydrochloride 25mg
A20308-1CNS-5161 hydrochloride 1mg
A20308-10mM-DCNS-5161 hydrochloride 10mM * 1mL in DMSO
BA8564-10CNS-11

Popular Products