SGE-516

• Target :

  Others|||GABA Receptor

• Related Pathways :

  Others|||Neuroscience|||Membrane transporter/Ion channel

• Bioactivity :

  SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against acute seizures and reduces neuronal cell death.

• Smiles :

  C[C@@]12[C@]([C@]3([C@](CC1)([C@@]4([C@](CC3)(C[C@](C)(O)CC4)[H])[H])[H])[H])(CC[C@@H]2C(CN5N=CC=N5)=O)[H]

• Molecular Formula :

  C23H35N3O2

• Molecular Weight :

  385.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1430064-74-6