STAT3-IN-24, cell-permeable

STAT3-IN-24, cell-permeable

• CAS Number: 400628-16-2
• UNSPSC Description: STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].
• Target Antigen: STAT
• Type: Peptides
• Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/stat3-in-24-cell-permeable.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](CC1=CC=C(C=C1)OP(O)(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]4NCCC4
• Molecular Weight: 1958.32
• References & Citations: [1]Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4(1):49-60.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported