IWP-2

• Target:

  Porcupine|||Casein Kinase|||Wnt/beta-catenin

• Related Pathways:

  Stem Cells|||Cytoskeletal Signaling|||Metabolism

• Purity:

  0.9976

• Bioactivity:

  IWP-2 is a Wnt pathway inhibitor (IC50=27 nM) and an ATP-competitive CK1? inhibitor (IC50=40 nM for M82FCK1?) . IWP-2 inhibits self-renewal of embryonic stem cells and has been used in stem cell and organoid research.

• Smiles:

  Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1

• Molecular Formula:

  C22H18N4O2S3

• Molecular Weight:

  466.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  686770-61-6