IWP-2

• Target :

  Porcupine|||Casein Kinase|||Wnt/beta-catenin

• Related Pathways :

  Stem Cells|||Cytoskeletal Signaling|||Metabolism

• Purity :

  0.9976

• Bioactivity :

  IWP-2 is a Wnt pathway inhibitor (IC50=27 nM) and an ATP-competitive CK1? inhibitor (IC50=40 nM for M82FCK1?) . IWP-2 inhibits self-renewal of embryonic stem cells and has been used in stem cell and organoid research.

• Smiles :

  Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1

• Molecular Formula :

  C22H18N4O2S3

• Molecular Weight :

  466.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  686770-61-6