IWP-3

• Target:

  Wnt/beta-catenin

• Related Pathways:

  Cytoskeletal Signaling|||Stem Cells

• Purity:

  0.9838

• Bioactivity:

  IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1?3 and CK1?, but does not inhibit CK1? [1] [2].

• Smiles:

  Cc1ccc2nc (NC (=O) CSc3nc4CCSc4c (=O) n3-c3ccc (F) cc3) sc2c1

• Molecular Formula:

  C22H17FN4O2S3

• Molecular Weight:

  484.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  687561-60-0