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Bim-BLK-A

CAT: 0931-T26817-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T26817-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others
Related Pathways
Others
Bioactivity
Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC) . Bim-BLK-A protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction.
Smiles
O=C1C=CC(C2=NC(S(=O)(C)=O)=NC(C(F)(F)F)=C2)=CN1CC3=CC=C(OC)C(OC)=C3
Molecular Formula
C20H18F3N3O5S
Molecular Weight
469.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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