BLK-IN-2

• Target:

  Others|||BTK

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Others

• Bioactivity:

  BLK-IN-2 is a potent, selective, and irreversible inhibitor of B-Lymphoid tyrosine kinase (BLK), demonstrating significant efficacy with an IC50 of 5.9 nM. Additionally, it exhibits an inhibitory effect on BTK (Bruton's tyrosine kinase) with an IC50 of 202.0 nM. This compound has shown strong antiproliferative activities against various lymphoma cells.

• Smiles:

  C(NC1=CC(C(NC=2C=NC(NC3=CC(NC4CCN(C(C=CCN(C)C)=O)CC4)=CC=C3)=NC2)=O)=C(C)C=C1)(=O)C5=CC6=C(C=C5)C=NC=C6

• Molecular Formula:

  C39H41N9O3

• Molecular Weight:

  683.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2694871-86-6