BLK-IN-2

CAT: 0931-MF-0146680-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146680-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2694871-86-6
Target
Others|||BTK
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
BLK-IN-2 is a potent, selective, and irreversible inhibitor of B-Lymphoid tyrosine kinase (BLK), demonstrating significant efficacy with an IC50 of 5.9 nM. Additionally, it exhibits an inhibitory effect on BTK (Bruton's tyrosine kinase) with an IC50 of 202.0 nM. This compound has shown strong antiproliferative activities against various lymphoma cells.
Smiles
C(NC1=CC(C(NC=2C=NC(NC3=CC(NC4CCN(C(C=CCN(C)C)=O)CC4)=CC=C3)=NC2)=O)=C(C)C=C1)(=O)C5=CC6=C(C=C5)C=NC=C6
Molecular Formula
C39H41N9O3
Molecular Weight
683.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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