Products for Research Use Only
RegisterLogin

BBR 2160

CAT: 0931-T26751-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T26751-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
118587-22-7
Target
Calcium Channel, Others
Related Pathways
Metabolism, Membrane transporter/Ion channel, Others
Bioactivity
BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on guinea-pig papillary muscle and sheep Purkinje fibres. BBR 2160 (10 (-7) and 10 (-6) M) dose dependently decreased the contractility of driven papillary muscle and Purkinje fibre. This effect was associated with a lowering of the plateau phase and a shortening of action potential duration in papillary muscle.
Smiles
C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1CSCCNC=O)C2=CC(N(=O)=O)=CC=C2
Molecular Formula
C21H25N3O7S
Molecular Weight
463.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Bbr 2160
CAS Number118587-22-7
PubChem CID195267
IUPAC Name3-O-ethyl 5-O-methyl 2-(2-formamidoethylsulfanylmethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular FormulaC21H25N3O7S
Molecular Weight463.5
XLogP2.3
Topological Polar Surface Area165
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count11
Heavy Atom Count32
Formal Charge0
Complexity791
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)CSCCNC=O
InChI
InChI=1S/C21H25N3O7S/c1-4-31-21(27)19-16(11-32-9-8-22-12-25)23-13(2)17(20(26)30-3)18(19)14-6-5-7-15(10-14)24(28)29/h5-7,10,12,18,23H,4,8-9,11H2,1-3H3,(H,22,25)
InChIKey
CLMNTOZRDYXVRT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Bbr 2160
CAS: 118587-22-7
CID: 195267
Formula: C21H25N3O7S
MW: 463.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight463.5
XLogP32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count11
Exact Mass463.14132132
Monoisotopic Mass463.14132132
Topological Polar Surface Area165 Ų
Heavy Atom Count32
Formal Charge0
Complexity791
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T74626-01BBR-BODIPY
T34461-01S 2160
T67949-01TMX-2164
T6441L-01CGS 21680
T69205-01GGTI-2166
T202323-01MCN-2165
T6441-01CGS 21680 Hydrochloride
TCL-00273-01CGS 21680 sodium
T28788-01SK-216
T206251-01MTX-216

Alternative Products

CatalogName
GTR19198139-01BBR 2160
596870S 2160
12-8483-250Anti-Human Metapneumovirus, Matrix Protein (HMPV-2160)
9117-2000Autoclave indicator tape, 1 inch x 2160 inch
9117-1000Autoclave indicator tape, 0.75 inch x 2160 inch
TR304712Factor XI (F11) Human shRNA Plasmid Kit (Locus ID 2160)
TL304712VFactor XI (F11) Human shRNA Lentiviral Particle (Locus ID 2160)
SR301505Factor XI (F11) Human siRNA Oligo Duplex (Locus ID 2160)
9152-2200Labeling tape, green, water resistant, 3/4 inch wide, 2160 inch long (19mm x 54.9m)
9152-2100Labeling tape, yellow, water resistant, 3/4 inch wide, 2160 inch long (19mm x 54.9m)

Popular Products