AM-1430

CAT: 0931-T26608-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T26608-01Size:100 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others
Related Pathways
Others
Bioactivity
AM-1430 is a potent and selective PI3K? inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB, u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.
Smiles
CNC(C1=C(C2=NC=CC=C2)C([C@H](C)NC3=NC=NC(N)=C3C#N)=NC4=CC=CC(F)=C14)=O
Molecular Formula
C23H19FN8O
Molecular Weight
442.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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