Filanesib TFA

• Target :

  Kinesin|||Others

• Related Pathways :

  Others|||Cytoskeletal Signaling

• Bioactivity :

  Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing.

• Smiles :

  C(C(O)=O)(F)(F)F.C(CCN)[C@@]1(N(C(N(OC)C)=O)N=C(S1)C2=C(F)C=CC(F)=C2)C3=CC=CC=C3

• Molecular Formula :

  C22H23F5N4O4S

• Molecular Weight :

  534.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1781834-99-8