Binimetinib

• Target :

  MEK|||Autophagy

• Related Pathways :

  Autophagy|||MAPK

• Purity :

  >99.99%

• Bioactivity :

  Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.

• Smiles :

  Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(cc12)C(=O)NOCCO

• Molecular Formula :

  C17H15BrF2N4O3

• Molecular Weight :

  441.23

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  606143-89-9