Binimetinib

• Target:

  MEK|||Autophagy

• Related Pathways:

  Autophagy|||MAPK

• Purity:

  >99.99%

• Bioactivity:

  Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.

• Smiles:

  Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(cc12)C(=O)NOCCO

• Molecular Formula:

  C17H15BrF2N4O3

• Molecular Weight:

  441.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  606143-89-9