Binimetinib

CAT: 0498-bs-83020C-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-83020C-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

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HY-15202R-01	Binimetinib (Standard)
SD5951-10mM	Binimetinib (MEK inhibitor)
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Binimetinib

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