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TP0427736

CAT: 0931-T24897-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T24897-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
864374-00-5
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Purity
0.9767
Bioactivity
TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-?-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse hair follicles.
Smiles
CC=1N=C(C2=C(NC=N2)C=3C=C4C(=CC3)N=CS4)SC1
Molecular Formula
C14H10N4S2
Molecular Weight
298.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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