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SIRT6-IN-5

CAT: 0931-T24793-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T24793-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
891002-11-2
Target
Sirtuin
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9923
Bioactivity
SIRT6-IN-5 (SIRT6 inhibitor 5) is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.SIRT6-IN-5 is immunosuppressive and chemo-sensitizing, increases H3K9 acetylation and glucose uptake in cultured cells, and reduces T-cell proliferation.
Smiles
N(C(=O)C1=CC=C(NC(=O)C2=CC=CO2)C=C1)C3=CC(C(O)=O)=C(O)C=C3
Molecular Formula
C19H14N2O6
Molecular Weight
366.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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