PF-249

CAT: 0931-T24626-05Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T24626-05Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1467059-70-6

Target

AMPK

Related Pathways

PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

Purity

0.9702

Bioactivity

PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.

Smiles

COc1nc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(O)=O)N(C)C

Molecular Formula

C17H16ClN3O3

Molecular Weight

345.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

6-chloro-5-(6-(dimethylamino)-2-methoxypyridin-3-yl)-1H-indole-3-carboxylic acid

CAS Number	1467059-70-6
PubChem CID	71767991
IUPAC Name	6-chloro-5-[6-(dimethylamino)-2-methoxy-3-pyridinyl]-1H-indole-3-carboxylic acid
Molecular Formula	C17H16ClN3O3
Molecular Weight	345.8
XLogP	3.5
Topological Polar Surface Area	78.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	24
Formal Charge	0
Complexity	464

SMILES

CN(C)C1=NC(=C(C=C1)C2=C(C=C3C(=C2)C(=CN3)C(=O)O)Cl)OC

InChI

InChI=1S/C17H16ClN3O3/c1-21(2)15-5-4-9(16(20-15)24-3)10-6-11-12(17(22)23)8-19-14(11)7-13(10)18/h4-8,19H,1-3H3,(H,22,23)

InChIKey

MJHBRTGGZYSCHJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1467059-70-6

CID: 71767991

Formula: C17H16ClN3O3

MW: 345.8

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	345.8
XLogP3	3.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	345.0880191
Monoisotopic Mass	345.0880191
Topological Polar Surface Area	78.5 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	464
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T85572-01	Acid Red 249
T9901A-1753-01	PF-04840082
T28360-01	PF-00489791
T16493-01	PF-06465469
T36017-01	PF-05381941

Alternative Products

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562066	PF-249
BA6075-5	LSP-249
596374	JWH-249
MBS5812913	FTI-249
MBS3847219-01	JWH 249
HY-162751	Anticancer agent 249
HY-159809-01	Antibacterial agent 249
RM-T060577-01	Tofacitinib Impurity 249
RM-A162649-01	Apixaban Impurity 249
HY-161883	JP-2-249

PF-249

Chemical Information

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