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MI-1481

CAT: 0931-T24463-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T24463-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1887178-64-4
Target
Epigenetic Reader Domain, Others
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
MI-1481 is an effective MML1 inhibitor (IC50: 3.6 nM) . MI-1481 showed very potent inhibition of the menin-MLL1 interaction (IC50: 3.6 nM) . MI-1481 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models.
Smiles
C(N1C=2C(C=C1C#N)=C(C)C(CN3CCC(NC4=C5C(SC(CC(F)(F)F)=C5)=NC=N4)CC3)=CC2)[C@@H]6CNC(=O)CO6
Molecular Formula
C29H30F3N7O2S
Molecular Weight
597.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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