MI-1481

• CAS Number :

  1887178-64-4

• Target :

  Epigenetic Reader Domain|||Others

• Related Pathways :

  Others|||Chromatin/Epigenetic

• Bioactivity :

  MI-1481 is an effective MML1 inhibitor (IC50: 3.6 nM) . MI-1481 showed very potent inhibition of the menin-MLL1 interaction (IC50: 3.6 nM) . MI-1481 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models.

• Smiles :

  C(N1C=2C(C=C1C#N)=C(C)C(CN3CCC(NC4=C5C(SC(CC(F)(F)F)=C5)=NC=N4)CC3)=CC2)[C@@H]6CNC(=O)CO6

• Molecular Formula :

  C29H30F3N7O2S

• Molecular Weight :

  597.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C