MI-192

• Target:

  Others|||Apoptosis|||HDAC

• Related Pathways:

  Apoptosis|||Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair

• Bioactivity:

  MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50 values of 30 nM and 16 nM, respectively. It exhibits greater selectivity for HDAC2/3 over other HDAC isomers and induces apoptosis in myeloid leukemic cells, indicating potential therapeutic use in leukemia and as an anti-stroke agent [1] [2].

• Smiles:

  O=C1C=2C(C(=C)CN1CC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=CC=CC2

• Molecular Formula:

  C24H21N3O2

• Molecular Weight:

  383.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1415340-63-4