MI-192

CAT: 0931-MF-0109890Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0109890Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415340-63-4
Target
Others|||Apoptosis|||HDAC
Related Pathways
Apoptosis|||Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair
Bioactivity
MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50 values of 30 nM and 16 nM, respectively. It exhibits greater selectivity for HDAC2/3 over other HDAC isomers and induces apoptosis in myeloid leukemic cells, indicating potential therapeutic use in leukemia and as an anti-stroke agent [1] [2].
Smiles
O=C1C=2C(C(=C)CN1CC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=CC=CC2
Molecular Formula
C24H21N3O2
Molecular Weight
383.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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