Products for Research Use Only
RegisterLogin

JTP-70902

CAT: 0931-T24222-03Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T24222-03Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
871696-49-0
Target
MEK, Others
Related Pathways
Others, MAPK
Bioactivity
JTP-70902 is a protein kinase inhibitor with antineoplastic activity.
Smiles
N(C=1C2=C(N(C(=O)N(C2=O)C3CC3)C4=CC(NS(C)(=O)=O)=CC=C4)N(C)C(=O)C1)C5=C(F)C=C(Br)C=C5
Molecular Formula
C24H21BrFN5O5S
Molecular Weight
590.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Jtp-70902

a protein kinase inhibitor and antineoplastic agent; structure in first source

CAS Number871696-49-0
PubChem CID11527186
IUPAC NameN-[3-[5-(4-bromo-2-fluoroanilino)-3-cyclopropyl-8-methyl-2,4,7-trioxopyrido[2,3-d]pyrimidin-1-yl]phenyl]methanesulfonamide
Molecular FormulaC24H21BrFN5O5S
Molecular Weight590.4
XLogP2.9
Topological Polar Surface Area128
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Heavy Atom Count37
Formal Charge0
Complexity1170
SMILES
CN1C(=O)C=C(C2=C1N(C(=O)N(C2=O)C3CC3)C4=CC=CC(=C4)NS(=O)(=O)C)NC5=C(C=C(C=C5)Br)F
InChI
InChI=1S/C24H21BrFN5O5S/c1-29-20(32)12-19(27-18-9-6-13(25)10-17(18)26)21-22(29)30(24(34)31(23(21)33)15-7-8-15)16-5-3-4-14(11-16)28-37(2,35)36/h3-6,9-12,15,27-28H,7-8H2,1-2H3
InChIKey
PDRPNIUQNAWRSA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Jtp-70902
CAS: 871696-49-0
CID: 11527186
Formula: C24H21BrFN5O5S
MW: 590.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight590.4
XLogP32.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass589.04308
Monoisotopic Mass589.04308
Topological Polar Surface Area128 Ų
Heavy Atom Count37
Formal Charge0
Complexity1170
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T32317Jtp 2942
T70093-01JTP 103237
T63636-01JTP-117968
T70365-01JTP-4819
T8951-01JTP 0819958 - HOIPIN-1

Alternative Products

CatalogName
MBS5773973JTP-70902
MBS5812636JTP 103237
MBS5812906JTP-4819
MBS3607010JTP-117968
MBS5781894Jtp 2942
HY-135505JTP-103237
MBS8506567-01GSK1120212 (JTP-74057)
MBS5765651JTP 0819958 - HOIPIN-1
MBS384815-01GSK1120212 (JTP-74057, Trametinib)
A11029-500GSK1120212 (JTP-74057, Trametinib) 500mg

Popular Products