J-104871

• Target:

  Ras|||Transferase

• Related Pathways:

  MAPK|||GPCR/G Protein|||Metabolism

• Purity:

  0.9903

• Bioactivity:

  J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.

• Smiles:

  C(O)(=O)C1(C(O)=O)O[C@H](C(N([C@@H]([C@H](C/C=C/C2=NC=3C(O2)=CC=CC3)C=4C=C5C(=CC4)OCO5)C)CC6=CC7=C(C=C6)C=CC=C7)=O)[C@H](C(O)=O)O1

• Molecular Formula:

  C38H32N2O12

• Molecular Weight:

  708.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  191088-19-4