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J-104871

CAT: 0931-T24188-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T24188-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
191088-19-4
Target
Ras, Transferase
Related Pathways
MAPK, GPCR/G Protein, Metabolism
Purity
0.9903
Bioactivity
J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
Smiles
C(O)(=O)C1(C(O)=O)O[C@H](C(N([C@@H]([C@H](C/C=C/C2=NC=3C(O2)=CC=CC3)C=4C=C5C(=CC4)OCO5)C)CC6=CC7=C(C=C6)C=CC=C7)=O)[C@H](C(O)=O)O1
Molecular Formula
C38H32N2O12
Molecular Weight
708.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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