J-1048

CAT: 0931-T78790-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T78790-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2374772-60-6

Target

ALK, Others

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Others

Bioactivity

J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/Smad signaling pathway [1].

Smiles

C(C(NC1=CC(F)=CC=C1)=S)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(C=C4)=NSN5

Molecular Formula

C23H17FN6S2

Molecular Weight

460.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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