J-1048

• Target :

  ALK|||Others

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Others

• Bioactivity :

  J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-?/Smad signaling pathway [1].

• Smiles :

  C(C(NC1=CC(F)=CC=C1)=S)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(C=C4)=NSN5

• Molecular Formula :

  C23H17FN6S2

• Molecular Weight :

  460.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2374772-60-6